In Fortuna, a group known as the Order of the Sword practices an elusive religion. They revere the demon warrior Sparda, who as their god fought to protect humans, and are committed to the extermination of all demons. Nero, a young knight from the Order, is tasked with finding Dante, the mysterious assassin who murdered the head of the Order of the Sword. Simultaneously, more demons begin to surface throughout the city. Nero soon comes to discover the motives behind Dante’s appearance and the truth behind the intentions of the Order of the Sword.